CBD for Pets!

Our friends at Flower Child wrote this great piece on using cannabis to treat your pets. Their CBD Tincture for Pets is available at both Substance locations. Of course, be sure to consult with a trusted veterinarian before giving medical marijuana to your pet.

Marijuana for Pets, Oh My!

Our pets mean the world to us, they fill our lives with happiness and laughter, they are loyal and never judge us, they forgive us and are always happy to see us. We love our pets. We want them to be happy and healthy and it’s awful when they are sick. It hurts us to see our pets suffering.

Cannabis has been used for thousands of years for it’s therapeutic qualities and as it becomes more and more accepted today for it’s medicinal benefits people are realizing that cannabis works wonders not only for humans but for our four legged friends as well. You got it. Medical marijuana for pets!

Some people may call the cannabis movement a trend or a craze, but this herb’s therapeutic properties are science-based fact. Oakland-based veterinarian Dr. Gary Richter tells us cannabis can be used on your pet to treat a variety of medical conditions including:

  • Allergies/ itching
  • Anxiety
  • Arthritis and other causes of pain
  • Appetite support
  • Cancer treatment
  • Cancer pain
  • Glaucoma
  • Inflammatory Bowel Disease
  • Quality of life / Hospice care
  • Seizures

But, we still have a lot to learn about cannabis in general and marijuana for pets is no different.

If you’re considering medical marijuana for pets, here are some important points you want to keep in mind.
And of course, be sure to consult with a trusted veterinarian before giving medical marijuana to your pet.

Pets have endocannabinoid systems, just like us humans

The endocannabinoid system is quickly gaining relevance in modern medicine for both humans and pets.
Just like humans, animals also have endocannabinoid systems (ECS). The ECS has receptors throughout the whole body. It is this system that helps us maintain balance in our body. If we are deficient in cannabinoids our body is out of whack so to speak. We are unbalanced.

Like us, animals produce their own cannabinoids to interact with and signal the ECS. And like us, animals also run into endocannabinoid deficiencies. This is where whole-plant-based cannabis medicine comes into play. Cannabis has cannabinoids which attach to our ECS and create balance and healing for those deficient in cannabinoids. It is almost as if this plant was created specifically to heal and balance our bodies.

Be very careful with dosing marijuana to your pet.

A marijuana overdose is not fatal, but it can be a traumatic experience as a pet owner. The general rule of thumb is this: give the smallest dose possible and gradually work your way up until you find the smallest yet most effective cannabis dosage level for your pet. But knowing exactly what dosage you’re giving your pet can be tricky, Richter says. And because many of the products on the market are highly potent and animals have a smaller body size, we have to be extra careful.

Signs of a pet marijuana overdose.

If your pet does experience a cannabis overdose, don’t let the mishap turn you away from this medicine completely. The therapeutic potential is still there if done properly. Too much THC can be extremely unpleasant, and with pets it’s really easy to overdo it if you’re not careful – or if you don’t know what you’re doing. So what does a pet overdose look like, and how do you know when to make a trip to the emergency clinic?

“A lot of it might be what you expect. The animal will start to look a little bit spacey and get a bit wobbly,” Richter says. “A lot of dogs will develop the syndrome called static ataxia, where basically they’re standing still and start to tip over but catch themselves before they fall.”

If the overdose is substantial enough, the pet’s blood pressure level may not be particularly stable or they won’t eat, Richter says. Even though these overdoses are not fatal they can be an extremely traumatic – not to mention pricey – experience for pets and families. Nobody wants to see their pet in that kind of condition. And the thing with edibles is that the effects can be really long-lasting, 12 hours or longer depending on how much has been consumed. It’s an experience that can turn pet owners away from marijuana for pets completely, even though there is still therapeutic potential if done properly. New research is showing that CBD can counteract the affects of a THC overdose, kind of an antidote.

Should you take your pet to the emergency clinic?

“If the dog is a little wobbly but seems comfortable, I would not necessarily advise a visit to the emergency room. If you are concerned however, it’s best to contact a veterinarian for advice,” Richter says. “If the pet is having a hard time standing and they’re not really responding properly and they’re not eating or drinking, then they probably need to be seen for that.”

Learn the methods of marijuana delivery for your pet.

Deciding which delivery method is best for your pet can take some research. Capsules, treats, tinctures, topicals – just like cannabis medicine for humans, we have a variety of options in delivering marijuana for pets. Richter has seen a lot of pet owners find success with cannabis oils, which they give their pet orally. He has also seen a cannabis topical spray clear up severe skin allergies in dogs, to the point where they stop scratching for 4 to 6 hours.

“Short of loading them up on a steroid like prednisone, nothing does that. This topical is nothing short of amazing,” Richter says.

Yet another method of delivery, although Richter has yet to see it applied to pets, is a cannabis suppository.

Figuring out THC-CBD ratios for pets.

With cannabis there are countless options to form the ultimate combination of strains, cannabinoids, and terpenes. This is an important part of cannabis medicine, especially because the amount of THC, CBD, and other cannabinoids, flavonoids, and terpenes can fluctuate wildly from one strain to another. Dr. Richter has seen success with varying ratios of THC and CBD depending on the condition being treated.

“Sometimes, higher concentrations of THC are more effective provided the product is dosed correctly,” he says. Finding the best ratio of marijuana for pets requires experimenting, trial and error – and of course safe access to products that are accurately and precisely labeled.

“It is always best to seek the advice of an experienced veterinary professional when deciding which product and what dose to use,” Richter says. Richter advises against CBD products where there is little to no THC – such as with a lot of the CBD hemp oils found online. “If you’re looking to treat a dog that maybe has minor soreness, there might be some positive effect with a hemp-based CBD product, but otherwise you’re severely restricting your therapeutic applications,” he says.

“With higher-end therapy for things like cancer, autoimmune disease, seizures, or even severe pain, you want a product that is made from cannabis – not hemp – that has a certain amount of THC in it.” The difference without THC in the mix, Richter says, is like the difference between shooting a bullet and throwing it.

Talk to your veterinarian about marijuana for pets.

Whether you live in a prohibition state or not, it’s okay to talk to your vet about marijuana for pets. The conversation has to start somewhere, and even if your veterinarian knows next to nothing about cannabis – that’ll change if enough people start asking.

“As cannabis becomes more available, you’re going to see people out there who will want to use it with their pets,” Richter says. “It’s going to be really important that somebody is able to provide people with guidance. There’s an opportunity here for education.”

If you are interested in using marijuana for pets, Flower Child recommends…

At FlowerChild CBD we recommend our CBD Tincture for Pets. This tincture has been specially formulated for animals with a very high CBD to THC ratio 25:1. It is a medicinal cannabis CBD not a industrial hemp CBD!

THC is what gets you high. CBD does not. THC is necessary in the blend to work synergistically with the CBD, but huge amounts of THC are not necessary to receive the medical benefits of the cannabis.

Help spread cannabis education by sharing this article with friends and followers. Who knows how many pets we might save.

ABOUT GARY RICHTER

Dr. Gary Richter is the owner and medical director of two award-winning veterinary hospitals in Oakland, California. His facilities, Montclair Veterinary Hospital and Holistic Veterinary Care provide both Western and complementary medicine for patients.

Dr. Richter approaches veterinary medicine with an “eyes open” strategy. He utilizes Western medicine, complementary and alternative care, and new, emerging therapies to achieve the best possible results. By incorporating modalities such as herbal/nutritional therapy, acupuncture, chiropractic, and hyperbaric oxygen with conventional medicine and surgery, Dr. Richter does more than treat disease – he promotes healing and wellness.

“There are many conditions that can only be treated with Western medicine and surgery,” says Dr. Richter. “But clearly Western medicine is not the solution to every problem. It would be a mistake for us to turn our backs on successful treatment options because they are not mainstream or widely accepted. There are many occasions when alternative therapy or a combination of therapies is the best solution. If optimal health and welfare is the goal, every legitimate option should be considered for every patient.”
Article by Green Flower Media – Gregory Frye

Distillate: The cannabis concentrate of the future

distillation | dis·til·la·tion | noun

a: the purification or concentration of a substance, the obtaining of the essence or volatile properties contained in it, or the separation of one substance from another, by such a process.

You may only remember this word from high school chemistry class, but distillation is quickly changing the cannabis industry. Concentrate producers are using innovative distillation techniques to create potent, pure, and clean cannabis distillates that can be dabbed, vaped, eaten, dropped under your tongue… the list goes on.

Where Does A Cannabis Oil Distillate Come From?

Pure, potent cannabis oil distillate does not just appear in the wild. There is a specific scientific process that takes place before users are presented with what may very well be the future of cannabis concentrates. In order to extract THC, terpenes, and other cannabinoids from the cannabis plant a solvent-based (butane, propane, CO2) extraction must be performed first.

The solvent-based extraction removes valuable compounds from the plant itself, however many other compounds remain in the extract. In order to distill down to a more pure form, further refinement is done through the processes of winterization and decarboxylation. Finally, the oil is run through a distillation chamber multiple times to refine the desirable compound (THC or CBD) to its most pure form.

Consuming Cannabis Oil Distillate

As we mentioned above, cannabis distillates have a wide variety of applications that can appeal to just about any type of user. Pure cannabis distillates contain virtually no flavors or aromas, which makes them perfect for practical applications where the cannabis “flavor” is not needed or wanted (think edibles and drinks!). Additionally, these powerful distillates have great medicinal potential because of the small amounts needed to produce strong effects.

With a potential potency of nearly 99%, cannabis oil distillate should not be taken lightly. Check out this simple graph below to get an idea of how potent distillate is compared to flower.

distillate-potency

Final Word

While cannabis distillate may be somewhat new to the concentrate market, this well-developed, scientific extraction technique looks to be the next gold standard for cannabis extraction and refinement. While we still love our BHO, CO2, and PHO dabs… cannabis oil distillate is certainly worth trying if you’re looking for the most pure, clean, and potent concentrate.

Cannabis Oil Cartridges: Are they for me?

The Good Kind Of Oil

As cannabis consumption continues to enter mainstream society, personal vaporizers are becoming more popular by the day. Vaporization is, essentially, the point at which solids turn to gas. In the cannabis world this means heating a product, but not to the point at which it burns.

There are many different types of vaporizers that allow users to vape dry herb, hash or wax, and oil via a pre-filled cartridge. Today, we will be discussing the increasingly popular oil cartridges.

Oil cartridges are pre-filled, ready to use, and are made with just about any strain you could want. The cartridge is connected to a battery and voila, you’re ready to vape! You might be asking yourself, “how did a leafy green flower turn into this golden oil, and how did it get into this cartridge?”

How Does A Flower Become An Oil?

Other than strain, the main consideration when choosing an oil cartridge is the method of extraction. Currently, there are two widely used solvents for extraction: carbon dioxide and butane. Each of these steps could be expanded on for pages, but the basic process is as follows:

  1. Flower is loaded into an extraction chamber.
  2. The chosen solvent (CO2 or butane) is used to perform the initial extraction which produces a “crude” oil.
  3. That “crude” oil is refined multiple times to filter out any unwanted materials and extract THC.
  4. Cartridges are filled either by hand or by a machine.

Carbon dioxide and butane both have their advantages and disadvantages when it comes to creating oil cartridges. At this early stage in the oil cartridge industry, comparing the two is like comparing iOS to Android – both camps have strong feelings and good points to make, and both are great options.

runny-honey

Benefits of Cannabis Oil Cartridges

Vaporizing cannabis via an oil cartridge has become a popular method of consumption for many users due to its ease of use, quick onset, discreteness, and medicinal benefits. Rather than fumbling with hash or wax and trying to reapply a dab of oil, a cartridge is always ready to go. Rather than eating an edible, which could take up to an hour to feel the effects, oil cartridges produce a vapor that is inhaled through your lungs and absorbed quickly for an onset time of less than 10 minutes. If being discrete is what you’re after, oil cartridges produce a light, nearly odorless vapor. Perhaps most importantly are the medicinal benefits for users who need to carefully control their dosages and cannot physically handle smoke or sugary edibles entering their bodies.

How To Use Cannabis Oil Cartridges

To use an oil cartridge you need three things: a battery, a battery charger, and a cartridge. 510 thread batteries have become the most popular form of battery, but be sure to ask your budtender about compatibility between a battery and cartridge. Once you’re home and ready to try out your new cartridge read the instructions on the battery. Battery functionality such as temperature control varies across brands, so be sure you’ve read the instructions and understand how to use your battery.

Come see us at either our Empire or Division locations to speak with a staff member about which cartridge is right for you!

Pro-tip: Don’t over do it. Short, repeated rips will offer better flavor, a reduced risk of burning the oil, and an overall better experience.

Happy Vaping!

cannabis oil cartridges

Cannabis Reactions

People often react very differently to cannabis consumption. For many, it’s a relaxing, even meditative experience, while others often feel anxious and paranoid. Some find a small, light dosage effective. Others need high quantities of extremely strong cannabis to feel any effects at all. So why do our reactions vary so widely? Today, we’ll explore a few fundamental components of our reactions to cannabis consumption.

The Endocannabinoid System

Our bodies process the cannabis plant through the endocannabinoid system. This system helps us maintain homeostasis. It works by producing endocannabinoids, natural chemicals that help our bodies with bioregulation. Endocannabinoids and the endocannabinoid system play a crucial role in regulating a variety of biological functions, including our reaction to chronic stress, nervous system functions, and even our body’s response to cancer.

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Image Source: http://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(15)00140-X

Cannabinoids are chemicals naturally secreted by the cannabis plant. They mirror the endocannabinoids produced by our body, and interact with the endocannabinoid system in a similar manner. These interactions help cause the plant’s psychoactive effects and therapeutic effects.

THC vs CBD

One of the most well known cannabinoids is tetrahydrocannabinol, or THC. This cannabinoid is primarily responsible for the high we associate with the cannabis plant. It also stimulates appetite, can reduce muscle spasms and vomiting, and relieves pain.  For some, THC can cause anxiety. Understanding your sensitivity to THC can help you better regulate the psychological effects you experience, and help you deal with any feelings of anxiety or paranoia.

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Image Source: http://www.weedist.com/2014/07/kick-paranoia-enjoy-cannabis-high/

You may also be familiar with cannabidiol, or CBD. Unlike THC, cannabidiol does not cause any psychoactive effects. It does, however, produce a wide variety of therapeutic benefits. Early research shows that it may be effective in treating several particularly difficult diseases, including multiple sclerosis, post traumatic stress disorder, and Crohn’s disease. It can also reduce anxiety, and may strengthen the painkilling effects of THC.

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Image Source: http://theleafonline.com/c/science/2014/08/cannabinoid-profiles-crash-course-cbga/

While THC and CBD are naturally found in the highest relative quantities of all the cannabinoids, it’s important to remember that there are over 100 different cannabinoids, and they all have different effects. Cannabinol, or CBN, for example, can induce sleep and help relieve pain. Additionally, because everyone has a different endocannabinoid system, different consumers experience some effects more strongly than others.

Other Factors

Cannabinoids are not the only factor at work in our reactions to cannabis. The essential oils of the cannabis plant, called terpenes, can alter the kind of psychoactive effects experienced, as well as what therapeutic benefits result.

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Image Source: https://www.leafly.com/news/cannabis-101/infographic-what-are-cannabis-terpenes-and-how-do-they-affect-you

Psychological factors are also important. How comfortable you feel with your environment, your mood while consuming cannabis, and what you expect to feel can alter the intensity of psychological effects and whether or not you experience anxiety. Gender may also be a factor — recent research indicates that women may be more sensitive to THC than men. As we explored today, we all experience cannabis differently. So take your time, and find out what works for you.

 

 

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Know Your Type: Cannabis Classifications

If you’re familiar with cannabis basics, you may have heard of two common terms used to describe different types of weed: indicas and sativas. These terms refer to two different species of marijuana, cannabis indica and cannabis sativa. Indicas and sativas look, smell, and taste different. Indicas tend to grow shorter and stockier, while sativas grow taller and thinner. Indica bud may have a purplish appearance.

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More fundamentally, these differences refer to the plant’s easily observable traits, or its phenotype. While they do correlate with certain effects — indicas are known for their stoney body highs, sativas for their more cerebral high — we’ll have to dig deeper to get a better understanding of what lies behind the many psychoactive effects and therapeutic benefits of the cannabis plant.

Phenotypes, Genotypes, and Chemotypes

We mentioned that a cannabis plant’s phenotype — its easily observable traits — tends to correlate with certain effects. But correlation doesn’t imply causation, so what causes those pleasing, therapeutic benefits that we associate with marijuana? To get a better understanding of what some of those causes may be, we’ll have to explore two additional terms: genotype and chemotype.

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A genotype is a living being’s genetic makeup. While phenotype refers to external, observable traits, genotype refers to the genetic, internal blueprint that a being inherits from its parents and ancestors. A genotype outlines the set of possible characteristics that a being could have or pass on to its offspring.

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Image Source: http://www.honest-essential-oils.com/eobbd-essential-oils/botanical-definition/

While a plant’s genotype refers to its genetic makeup, its chemotype refers to its chemical makeup. That is, what chemical compounds are most prevalent and in what combinations.

Cannabis Types

As noted above, indica and sativa refer to different phenotypes of the cannabis plant. More accurately, they refer to different phenotypic expressions. The plant’s genotype is what outlines the possibilities of what it can taste, smell, look, and feel like, and its phenotype is what actually shows up. That means that even if a plant has a strongly indica-like appearance and smell, it may still be storing some sativa genetics, or vice versa. This can lead to unexpected effects. With the ever-expanding range of hybrid strains out there, mixed genetics are also becoming more and more common, and mixed effects along with them.

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Image source: http://www.bestfriendsamsterdam.com/wp-content/uploads/indica_vs_sativa.png

Chemotypes in cannabis refer specifically to its THC versus its CBD content. These are two of the better-known cannabinoids, one of the main “active ingredients” in cannabis. Cannabis comes in three different chemical variations, or chemotypes. Type I refers to the so-called “drug type”, meaning that its high THC to low CBD ratio induces psychoactive effects, as well as other therapeutic benefits. Type III refers to the “fiber” or “non-drug type”, also often called hemp, because its high CBD to low THC ratio means that it induces little-to-no psychoactive effects, although it can still offer many therapeutic benefits. Type II is a sort of intermediate.

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A hemp field. Photo credit: Barbetorte – Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=7558724

While these basic chemotypes are helpful for understanding some of the effects a particular strain may have, it is important to remember that there are at least 85 different cannabinoids in the cannabis plant, and that they produce different therapeutic benefits. Cannabinoids are not the only factor at work, either. Terpenes, the essential oils of the cannabis plant that give it particular smells, also play an important role in cannabis’ psychoactive effects and therapeutic benefits.

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Image source: https://s3.amazonaws.com/leafly/content/cannabinoids-101-what-makes-cannabis-medicine/PLUe6NdETsirqg7Y9Hkf_Cannabinoid-Wheel-(Final)—English.jpg

We hope this breakdown has helped you understand what you’re getting with any one strain, and will help you find what works for you.

Cannabis Ingestion Methods: Dabbing

In our previous two posts, we covered two of the more common methods of consuming cannabis: smoking and vaping. Today, we’ll be moving in a newer and more powerful direction: dabbing.

What is it?

If you have heard of dabbing, you probably know something about its potency. For cannabis, the word ‘dabbing’ comes from ‘dab’, as in, “A dab’ll do ya”. Dabbing has much stronger effects than either smoking or vaping. Dabs hit considerably harder, and they tend to last much longer, too.

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Image source: https://www.leafly.com/news/cannabis-101/how-to-dab-cannabis-concentrates

Part of the reason dabs are so potent is because of what they are made of. Dabbing refers to a particular way to consume extracts, also called concentrates. These products are so strong because they have high concentrations of cannabinoids — what might be considered the main ‘active ingredient’ in weed. They are produced when solvents strip away much of the cannabis plant itself, but leave large amounts of the cannabinoids behind (and hopefully some terpenes, too).

How do you consume them?

Dabs are consumed using a dab rig. This contraption usually looks something like a bong (though not always). To smoke from a dab rig, a ‘dab’ of extract is lowered onto a super-heated nail — this is where one would find the ‘bowl’ when smoking flower from a bong.

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Image source: https://www.smokecartel.com/pages/infographic-anatomy-of-a-concentrate-rig

The extreme heat of the nail causes the concentrate to vaporize, rather than combust. The consumer then breathes the vapor in from the pipe. Combined with the already highly concentrated cannabinoid content, this method tends to hit harder than just about any other.

Dabbing vs other methods

The main difference between dabbing and smoking or vaping is that dabbing is simply stronger. That does not mean, however, that your tolerance or how high you want to be are the only factors at work. For those with severe medical needs, such as chronic pain or severe nausea, dabbing may be the only method capable of delivering effective relief.

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Additionally, a high cannabinoid content does not exclusively mean a high THC content. Many concentrates focus on high CBD content instead, and some shoot for a more balanced cannabinoid profile, creating different therapeutic effects and serving different medical needs. Of course, whatever your preference, it’s important to be sure that you know what works for you.

Cannabis Ingestion Methods: Smoking

With the sea of cannabis consumption options the average weed consumer faces today, sometimes it can be hard to know where to start, or how. That’s why here at Substance, we’re offering a quick guide to all the basic info you’ll need to get started. In our last post, we covered vaping. Today, we’ll be covering an old but reliable method: smoking your weed.

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For the purpose of this article, smoking will refer specifically to smoking flower, or bud. This would be the ‘weed’, ‘marijuana’, or ‘ganja’ that probably springs to mind when you think of cannabis. We will cover smoking concentrates, often called dabbing, in a later post.

The Basics

Before we talk about the method itself, let’s discuss the effects. Smoking has a near immediate onset. You will begin feeling its effects almost instantaneously, and it shouldn’t take more than 30 minutes to set in at the most. However, smoking is not as long lasting or as intense as other intake methods. The effects should last between 1 to 2 hours, and should be milder than edibles or dabbing.

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There are of course many ways to smoke. For any method, it’s important to grind your weed ahead of time. This will allow your weed to be as potent as possible, and will help you easily load and prepare it.

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Rolling

Joints, jays, spliffs, and blunts might be the most commonly known smoking methods. These all refer to different forms of marijuana cigarettes, so to speak.

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Image Source: http://www.wikihow.com/Roll-a-Marijuana-Joint

A joint or a jay is rolled with the same paper as a hand-rolled cigarette. It usually contains a crutch, that is, a small piece of stiff paper used to hold the joint together. You can purchase crutches made for hand rolling cigarettes, or you can make them from whatever you have on hand, such as a strip of a business card or cardboard paper. A joint or a jay will only contain cannabis.

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Image Source: https://cannabistutorials.com/how-to-roll-a-blunt/

A blunt, like a joint, only contains cannabis. However, it is rolled using special tobacco paper. Blunts generally do not use a crutch.

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Image Source: https://www.leafly.com/news/cannabis-101/what-is-a-spliff-and-why-would-you-smoke-one

A spliff, on the other hand, mixes tobacco with the weed itself. A spliff is also rolled with the same paper as cigarettes, and looks identical to a joint, except for what’s inside. While some may prefer a nice jay for the purely cannabis-based high, others prefer to spliff their weed to add a tobacco buzz and help cut costs.

Bowls

For those more keen on smoking their weed in bowls, there’s pieces and bongs. A piece is a small glass handheld pipe used for smoking marijuana,

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while a bong is a sort of glass water pipe.

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Of all the above methods, a bong is probably the most potent. Of course, everyone’s system is different, so be sure to take your time and figure out what works for you.

Bud Basics

For those of you new to cannabis, what’s inside of any variety of ganja can be a bit overwhelming. To help you navigate the sometimes seemingly endless array of weed-related jargon, we’ve prepared an intro for you on the primary source of all your favorite cannabis products: bud, or flower.

What is it?

Bud is the literal flower of the cannabis plant, thus why you may hear it called both bud and flower. It contains weed’s active ingredients: cannabinoids and terpenes.

bud

Cannabinoids and the ECS

Cannabinoids are the chemicals secreted by the cannabis plant. Most people are familiar with the cannabinoid tetrahydrocannabinol, or THC, as it plays a primary role in cannabis’ psychoactive effects (it gets you stoned). However, there are actually at least 85 cannabinoids, each with a variety of psychoactive effects and/or therapeutic benefits. Cannabinoids interact with your body via the endocannabinoid system, or ECS.

THC
Tetrahydrocannabinol, or THC

The ECS is endogenous to the human body. Your body produces its own version of cannabinoids: endocannabinoids. These help your body maintain homeostasis. How cannabinoids interact with your ECS and the endocannabinoids it produces will help determine both what kind of high you will get and what other therapeutic benefits the plant might yield.

Terpenes

Terpenes are the essential oil of the cannabis plant. They’re what give each variety of bud its own distinctive smell. Terpenes affect the way in which cannabinoids interact with your ECS. They can alter your high, or provide additional therapeutic effects.

Inforgraphic courtesy of Leafly. Find the original image and full article at: https://www.leafly.com/news/cannabis-101/infographic-what-are-cannabis-terpenes-and-how-do-they-affect-you/

Species

Cannabis intended for human consumption comes in two different species: Cannabis sativa and Cannabis indica. The third species, Cannabis ruderalis, contains too little cannabinoids and terpenes to be of much interest for cannabis consumers. These species refer to the plant’s phenotype — its easily observable traits, such as its appearance, smell, etc. Generally, sativas are known for their cerebral effects, and indicas for their soothing body effects.

illustration of the three types of the cannabis or marijuana plant - indica, sativa, ruderalis

However, since indica and sativa refer to the plant’s external, easily observable traits (and not its cannabinoid and terpene composition or its genetic makeup), it’s hard to say the exact effect of a cannabis plant of either species. Further, most cannabis today is some combination of the two, often referred to as a ‘hybrid’.

Strains

The strain of any cannabis plant refers to its genealogy (its parents, grandparents, etc.) A plant’s strain will tell you if it is an indica, sativa, or a combination of both. They are also generally indicative of its cannabinoid and terpene content, although this varies considerably from grower to grower.

Bud from the 'Blue Magoo' strain of cannabis.
Bud from the ‘Blue Magoo’ strain of cannabis.

We hope you’ve found this intro helpful. Keep an eye out for further introductory posts on different cannabis products and ingestion methods, and don’t forget to stop by Substance soon to put your weed knowledge to work!

Cannabis Supplements: Caring for Your ECS

As you may know, the effects of cannabis are due to its interaction with the endocannabinoid system (ECS). This is the system by which cannabinoids, the chemical compounds secreted by the cannabis plant, interact with the human body. The ECS helps the human body maintain homeostasis, meaning that it remains constant, well-regulated, and healthy.

Image Source: http://www.cell.com/action/showImagesData?pii=S1043-2760%2815%2900140-X

It was previously believed that the cannabis plant was the only source of cannabinoids. However, evidence is beginning to suggest that this may not be the case, and that there may be other ways to care for your ECS. In a recent paper, neurologist and pharmacology researcher Dr. Ethan Russo highlighted how some plants may be able to supplement the ECS. Below, we have outlined how some of these plants may help your body stay in balance.

ECS Receptors:
CB1 and CB2

The endocannabinoid system has two types of receptors: CB1 and CB2. CB1 receptors are found primarily in the brain and central nervous system, although they are found in other tissues to a lesser degree. CB2 receptors, by contrast, are found primarily in peripheral organs, especially in cells associated with the immune system.

Image Source: http://www.fundacion-canna.es/
Image Source: http://www.fundacion-canna.es/

CB1 Stimulators

To provide your CB1 receptors with some extra care, consider consuming frankincense or kava. Frankincense displays anti-inflammatory, antioxidant, and antiseptic effects similar to those of cannabis. It can be purchased as an essential oil and consumed by applying to the skin, usually with the help of a carrier oil, or inhaled. Large quantities can be toxic, however, so take care when inhaling.

Frankincense, before being made into an essential oil
Frankincense, before being made into an essential oil

Kava, a root native to the South Pacific islands, can produce calming effects similar to cannabis. It is usually consumed as a tea or tincture, and can be found at most herbalists. While there were concerns over one particular preparation causing liver damage in the past, this preparation is no longer commercially available, and Dr. Russo notes that it has a long history of safe use in Polynesia.

Fijian kava ceremony, performed for tourists Image Source: Jaejay77 - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=50488596
Fijian kava ceremony, performed for tourists
Image Source: Jaejay77 – Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=50488596

CB2 Stimulators

As it turns out, a variety of household items and commonly used plants may contain an agent of use to your ECS: beta-caryophyllene. Because of the way it interacts with your CB2 receptors, beta-caryophyllene has anti-inflammatory properties. It can be found in black pepper, lemon balm, cloves, and hops (which is, of course, used to prepare beer).

Black pepper is particularly rich in beta-caryophyllene
Black pepper is particularly rich in beta-caryophyllene

These are just a few of the non-cannabis plants that may help care for your ECS. For a complete overview, check out this interview with Dr. Russo. Don’t forget, however, that nothing stimulates your endocannabinoid system like cannabis itself, so be sure to stop by Substance soon!

Lesser-Known Cannabinoids: CBN

As you may know, many of the effects of the cannabis plant are due to the chemical compounds it secretes, called cannabinoids. While almost everyone is familiar with the cannabinoid tetrahydrocannabinol, or THC, there are actually over 100 cannabinoids. Recent popular and scientific interest in the therapeutic effects of cannabidiol, or CBD, has brought long-overdue attention to some of these other, lesser-known cannabinoids. Today, we’ll be taking a look at one of them: cannabinol, or CBN.

Where does it come from?

Cannabinol is a product of degradation. When cannabis oxidizes, THCA, the precursor to THC, degrades and forms CBNA. Oxidation occurs naturally with time, or with exposure to the air.

conversions
Image Source: https://www.medicaljane.com/2013/08/19/cannabinol-cbn-will-put-you-to-bed/

For this reason, poorly-cared for and older bud will often have higher concentrations of CBNA. Upon exposure to heat or UV rays — that is, when you smoke it or leave it in the sun –, CBNA then becomes CBN.

CBN and sleep

CBN and CBN-rich strains are known for inducing sleep. For those of you with insomnia or other sleep-related problems, CBN-heavy bud could be a good solution.

http://shawellnessclinic.com/shamagazine/wp-content/uploads/insomnia.jpg

Indica and indica-dominant strains are also known for their sleep-inducing qualities. Researchers believe that this may be due in part to their tendency to have higher concentrations of CBN.

Indica Strains of Cannabis

As we explored in our last post, some non-cannabis plants may also be beneficial for the endocannabinoid system. Some may also act synergistically with cannabis and cannabinoids. CBN, for example, tends to be a more effective sleep aid when consumed alongside hops, lavender, and chamomile.

Image Source: GFDL 1.2, https://commons.wikimedia.org/w/index.php?curid=322384
A lavender flower
Image Source:
GFDL 1.2, https://commons.wikimedia.org/w/index.php?curid=322384

Other therapeutic effects

CBN is also known to be anti-bacterial. Studies have shown its potential use as a topical in treating MRSA, an infection caused by a type of staph bacteria that has developed resistance to many traditional antibiotics.

Scanning electron micrograph of a human neutrophil ingesting MRSA
Scanning electron micrograph of a human neutrophil ingesting MRSA

It may also aid in bone-growth. Further research is needed, but it has demonstrated potential to help treat osteoporosis and aid the recovery of broken bones.

Image Source: BruceBlaus - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=46602308
Image Source:
BruceBlaus – Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=46602308

As the body of research on cannabis grows, we will likely continue to discover therapeutic benefits of CBN and other cannabinoids. Here at Substance, we hope to continue to seeing roadblocks to this kind of meaningful cannabis research removed.